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phenobarbital will lessen the level or effect of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers might lessen partiaprevir and ritonavir levels, and for that reason lessened efficacy of Viekira PakAntigen Description Barbiturates certainly are a cl